This process produces ammonia, which is eventually excreted in the urine as urea.
Normally, the liver breaks down the amino acid building blocks of protein to separate out the nitrogen they contain. These concerning signs appear because the liver is less and less able to metabolize protein properly. Frequently, a liver biopsy will be necessary to assess the exact nature of the situation as well as the extent of disease. If you see any of those signs, it’s obviously an emergency, and the dog has to be evaluated right away. Heinze says - seizures, and staring at the wall or even pressing her head into the wall. They include the dog’s walking as if she is drunk, feeling really sleepy after meals - “kind of spacy or zoned out,” Dr. Some dogs with advanced liver disease can show signs of “hepatic encephalopathy,” which basically means a problem with the brain related to the liver.
One of the two reasons to change a dog’s diet in the event that she has liver disease is that the disease has become severe, meaning the dog has essentially gone into liver failure and that organ is no longer able to do what it’s supposed to - filter toxins from body tissues and serve as the “control panel” for metabolism.
When the liver disease is severe and the dog has protein intolerance “But a change in liver enzyme values on blood work does not necessarily mean that a dietary change is appropriate.” Indeed, there are only two main instances where dietary change has been shown to be beneficial for liver disease. “A lot of owners want to change their dog’s diet if they see any signs” that something’s not right with the liver, says Tufts veterinary nutritionist Cailin Heinze, VMD, DACVM.
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